Oxytocin and vasopressin in posttraumatic stress disorder
The project comprises a meta-analysis and several empirical studies on the interactions between arginine vasopressin, oxytocin and posttraumatic stress disorder (PTSD). We differentiate the impact of traumatic events and PTSD symptoms on possible dysregulations of these endocrine systems. In addition, we are interested to explore the impact of both neuropeptides in phases of symptom changes. This involves the development of PTSD symptoms immediately after exposure to a traumatic event as well as psychotherapeutic treatment of PTSD.
Publications: Engel, S., Klusmann, H., Laufer, S., Pfeifer, A., Ditzen, B., van Zuiden, M., Knaevelsrud, C. & Schumacher, S. (2019). Trauma exposure, posttraumatic stress disorder and oxytocin: A meta-analytic investigation of endogenous concentrations and receptor genotype. Neuroscience & Biobehavioral Reviews. S0149-7634(19), 30046-30046.