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M.Sc. Manuel Heinrich

Manuel Heinrich Bild

Clinical Psychological Intervention

Research Assistant (externally funded project)

Schwendenerstr 27
Room 110
14195 Berlin
  • 2017: Master of Science in Psychology, Freie Universität Berlin

      • Master Thesis: Giving G a meaning. The Application of the Bifactor-(S-1) approach to realize a more symptom-oriented modeling of the Beck Depression Inventory.

  • 2015: Bachelor of Science in Psychology, Freie Universität Berlin

      • Bachelor Thesis: Does pre-interventional perceived social support predict inter-individual difference in early intra-individual change of depressive symptom load in a randomized controlled trial of internet delivered cognitive-behavioural therapy?

  • 2012 – Bachelor of Arts in Rehabilitation Education, Humboldt Universität Berlin

      • Bachelor Thesis: Depressive Störungen bei Menschen mit intellektueller Behinderung – Eine Übersicht.


Academic Career

Since März 2016 Rearch assistant

Freie Universität Berlin - Division of Clinical Psychological Intervention


2012 – 2016 Student research assistant

Psychiatric institute ambulance for adults with mental disability and mental illness, evangelic hospital Königin Elisabeth Herzberge, Berlin.

Peer-reviewed articles


Boettcher, J., Heinrich, M., Boettche, M., Burchert, S., Glaesmer, H., Gouzoulis-Mayfrank, E., Heeke, C., Hernek, M., Knaevelsrud, C., Konnopka, A., Muntendorf, L.-K., Nilles, H., Nohr, L., Pohl, S., Paskuy, S., Reinhardt, I., Sierau, S., Stammel, N., Wirz, C., Renneberg, B., & Wagner, B. (2024). Internet-based transdiagnostic treatment for emotional disorders in Arabic- and Farsi-speaking refugees: study protocol of a randomized controlled trial. Trials 25(13). https://doi.org/10.1186/s13063-023-07845-5

Als Preprint veröffentlicht: https://www.researchsquare.com/article/rs-2626858/v1

Brose, A.*, Koval, P.*, Heinrich, M., Zagorscak, P., Bohn, J., & Knaevelsrud, C. (in press). Location-scale modeling as an integrative approach to symptom dynamics during psychotherapy: An illustration with depressive symptoms. Journal of Consulting and Clinical Psychology.

Riecke, A.,* Klusmann, H.,* Heinrich, M., Haering, S., Blecker, M. K., Knaevelsrud, C.# & Schumacher, S.# (2024). Taube Menschen in Deutschland: Mental Health Literacy und Einschätzung der Angebote des psychiatrisch-psychotherapeutischen Versorgungssystem – eine Online Studie. [Deaf people in Germany: mental health literacy and perception of mental health services.] Verhaltenstherapie. 1–11. https://doi.org/10.1159/000535009 *Shared first authorship, #Shared last authorship


Brose, A.*, Heinrich, M.*, Bohn, J., Kampisiou, C., Zagorscak, P., & Knaevelsrud, C. (2023). Sequencing effects of behavioral activation and cognitive restructuring in an internet-based intervention for depressed adults are negligible: Results from a randomized controlled trial. Journal of Consulting and Clinical Psychology, 91(3), 122–138. https://doi.org/10.1037/ccp0000789


Tergeist, M., Ziegler, M., Heinrich, M., Sappok, T., & Bergmann, T. (2022). MUSAD-Short–A music-based screening tool to assess autism spectrum disorder in people with intellectual disability. Research in Autism Spectrum Disorders, 95, 101971. https://doi.org/10.1016/j.rasd.2022.101971


Böttche, M., Wagner, B., Vöhringer, M., Heinrich, M., Stein, J., Selmo, P., Stammel, N., & Knaevelsrud, C. (2021). Is only one cognitive technique also effective? Results from a randomised controlled trial of two different versions of an internet-based cognitive behavioural intervention for post-traumatic stress disorder in Arabic-speaking countries. European Journal of Psychotraumatology. 12(1). https://doi.org/10.1080/20008198.2021.1943870

Fenski, F., Rozental, A., Heinrich, M., Knaevelsrud, C., Zagorscak, P., & Boettcher, J. (2021). Negative effects in internet-based interventions for depression: A qualitative content analysis. Internet Interventions, 26, 100469. https://doi.org/10.1016/j.invent.2021.100469

Furukawa, T. A., Suganuma, A., Ostinelli, E. G., ..., Zagorscak, P., Knaevelsrud, C., Heinrich, M., ..., & Cuijpers, P. (2021). Dismantling, optimising, and personalising internet cognitive behavioural therapy for depression: a systematic review and component network meta-analysis using individual participant data. The Lancet Psychiatry, 8(6), 500-511. https://doi.org/10.1016/S2215-0366(21)00077-8

Karyotaki, E., Efthimiou, O., Miguel, C., genannt Bermpohl, F. M., Furukawa, T. A., Cuijpers, P., ... , Heinrich, M., .... & Forsell, Y. (2021). Internet-Based Cognitive Behavioral Therapy for Depression: A Systematic Review and Individual Patient Data Network Meta-analysis. JAMA psychiatry, 78(4), 361. https://doi.org/10.1001/jamapsychiatry.2020.4364

Schaeuffele, C., Heinrich, M., Behr, S., Fenski, F., Hammelrath, L., Zagorscak, P., Jansen, A., Pohl, S., Boettcher, J., & Knaevelsrud, C. (2022). Increasing the effectiveness of psychotherapy in routine care through blended therapy with transdiagnostic online modules (PsyTOM): Study protocol for a randomized controlled trial. Trials, 23(1), 830. https://doi.org/10.1186/s13063-022-06757-0


Boettcher, J., Weinbrecht, A., Heinrich, M., & Renneberg, B. (2020). Treatment of Social Anxiety Disorder and Avoidant Personality Disorder in Routine Care: A Naturalistic Study of Combined Individual and Group Therapy. Verhaltenstherapie, 1-9. https://doi.org/10.1159/000497738

Heinrich, M., Geiser, C., Zagorscak, P., Burns, G. L., Bohn, J., Becker, S. P., Eid, M., Beauchaine, T. P., & Knaevelsrud, C. (2020). On the Meaning of the General Factor of Psychopathology (“P-Factor”) in Symmetrical Bifactor Models. Preprint: https://doi.org/10.31234/osf.io/syj9k

Sappok, T., Heinrich, M., & Böhm, J. (2020). The impact of emotional development in people with autism spectrum disorder and intellectual developmental disability. Journal of Intellectual Disability Research, 64(12), 946-955. https://doi.org/10.1111/jir.12785

Zagorscak, P., Heinrich, M., Schulze, J., Böttcher, J., & Knaevelsrud, C. (2020). Factors contributing to symptom change in standardized and individualized Internet-based interventions for depression: A randomized-controlled trial. Psychotherapy, 57(2), 237-251. https://doi.org/10.1037/pst0000276


Bergmann, T., Heinrich, M., Ziegler, M., Dziobek, I., Diefenbacher, A., & Sappok, T. (2019). Developing a Diagnostic Algorithm for the Music-Based Scale for Autism Diagnostics (MUSAD) Assessing Adults with Intellectual Disability. Journal of Autism and Developmental Disorders, 49, 3732-3752. https://doi.org/10.1007/s10803-019-04069-y

Böhm, J., Diefenbacher, A., Heinrich, M., & Sappok, T. (2019). Autismusspektrumstörungen bei Erwachsenen mit Intelligenzminderung. Der Nervenarzt90(5), 490-496. https://doi.org/10.1007/s00115-018-0635-9

Sappok, T., Böhm, J., Birkner, J., Roth, G., & Heinrich, M. (2019). How is your mind-set? Proof of concept for the measurement of the level of emotional development. PloS one14(4), e0215474. https://doi.org/10.1371/journal.pone.0215474

Schumacher, S., Schopka, N. M., Heinrich, M., & Knaevelsrud, C. (2019). The German adaptation of the Therapist Beliefs about Exposure Scale: A validation study among licensed cognitive behavioural therapists in Germany. Behavioural and Cognitive Psychotherapy47(2), 164-180. https://doi.org/10.1017/S1352465818000371

Zagorscak, P., Bohn, J., Heinrich, M., Kampisiou, C., & Knaevelsrud, C. (2019). Nur auf Einladung? Wie die Rekrutierungsstrategie beeinflusst, wer online behandelt wird. Verhaltenstherapie29(3), 196-204. https://doi.org/10.1159/000502018

Zagorscak, P., Heinrich, M., Bohn, J., Stein, J. & Knaevelsrud, C. (2019). How individuals change during internet-based interventions for depression: A randomized controlled trial comparing standardized and individualized feedback. Brain and Behavior, 10(1), e01484. https://doi.org/10.1002/brb3.1484


Kruse, B., Heinrich, M., Diefenbacher, A., Kaiser, H., & Sappok, T. (2018). Demenz bei Down-Syndrom: Ein häufiger psychiatrischer Vorstellungsgrund. Fortschritte der Neurologie Psychiatrie86(07), 402-409. https://doi.org/10.1055/s-0043-124592

Heinrich, M., Zagorscak, P., Eid, M., & Knaevelsrud, C. (2018). Giving G a Meaning: An Application of the Bifactor-(S-1) Approach to Realize a More Symptom-Oriented Modeling of the Beck Depression Inventory–II. Assessment. https://doi.org/10.1177/1073191118803738

Zagorscak, P., Heinrich, M., Sommer, D., Wagner, B., & Knaevelsrud, C. (2018). Benefits of Individualized Feedback in Internet-Based Interventions for Depression: A Randomized Controlled Trial. Psychotherapy and Psychosomatics, 87(1), 32-45. https://doi.org/10.1159/000481515

Zagorscak, P., Heinrich, M., Sommer, D., Wagner, B., & Knaevelsrud, C. (2018). Reply to the Letter by Singer, Mitter, and Porsch Related to Our Paper “Benefits of Individualized Feedback in Internet-Based Interventions for Depression: A Randomized Controlled Trial”. Psychotherapy and Psychosomatics87(6), 367-368. https://doi.org/10.1159/000493394

Zagorscak, P., Schultze‐Krumbholz, A., Heinrich, M., Wölfer, R., & Scheithauer, H. (2018). Efficacy of Cyberbullying Prevention on Somatic Symptoms - Randomized Controlled Trial Applying a Reasoned Action Approach. Journal of Research on Adolescence, 29(4), 908-923. https://doi.org/10.1111/jora.12429


Derks, O., Heinrich, M., Brooks, W., Sterkenburg, P., McCarthy, J., Underwood, L., & Sappok, T. (2017). The Social Communication Questionnaire for adults with intellectual disability: SCQ-AID. Autism Research, 10(9), 1481-1490. https://doi.org/10.1002/aur.1795

Franke, M. L., Heinrich, M., Adam, M., Sünkel, U., Diefenbacher, A., & Sappok, T. (2017). Körpergewicht und psychische Erkrankungen. Der Nervenarzt, 89, 552-558. https://doi.org/10.1007/s00115-017-0411-2

Heeke, C., Stammel, N., Heinrich, M., & Knaevelsrud, C. (2017). Conflict-related trauma and bereavement: exploring differential symptom profiles of prolonged grief and posttraumatic stress disorder. BMC Psychiatry, 17(1), 118. https://doi.org/10.1186/s12888-017-1286-2

Heinrich, M., Böhm, J., & Sappok, T. (2017). Diagnosing Autism in Adults with Intellectual Disability: Validation of the DiBAS-R in an Independent Sample. Journal of Autism and Developmental Disorders, 48, 341-350. https://doi.org/10.1007/s10803-017-3336-5


Bergmann, T., Diefenbacher, A., Heinrich, M., Riedel, A., & Sappok, T. (2016). Multiprofessionelle Autismusdiagnostik bei erwachsenen Menschen mit Intelligenzminderung. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie, 64, 257-267. https://doi.org/10.1024/1661-4747/a000287

Mutsaerts, C. G., Heinrich, M., Sterkenburg, P. S., & Sappok, T. (2016). Screening for ASD in adults with ID - moving toward a standard using the DiBAS‐R and the ACL. Journal of Intellectual Disability Research60(5), 512-522. https://doi.org/10.1111/jir.12290

Sappok, T., Barrett, B. F., Vandevelde, S., Heinrich, M., Poppe, L., Sterkenburg, P., Vonk, J., Kolb, J., Claes, C., Bergmann, T., Došen, A., & Morisse, F. (2016). Scale of emotional development - Short. Research in Developmental Disabilities59, 166-175. https://doi.org/10.1016/j.ridd.2016.08.019

Sappok, T., Brooks, W., Heinrich, M., McCarthy, J., & Underwood, L. (2016). Cross-Cultural Validity of the Social Communication Questionnaire for Adults with Intellectual Developmental Disorder. Journal of Autism and Developmental Disorders, 47, 393-404. https://doi.org/10.1007/s10803-016-2967-2


Bergmann, T., Sappok, T., Diefenbacher, A., Dames, S., Heinrich, M., Ziegler, M., & Dziobek, I. (2015). Music-based Autism Diagnostics (MUSAD) - A newly developed diagnostic measure for adults with intellectual developmental disabilities suspected of autism. Research in Developmental Disabilities43-44, 123-135. https://doi.org/10.1016/j.ridd.2015.05.011

Elstner, S., Diefenbacher, A. & Heinrich, M. (2015). Etablierung eines Modells zur Beurteilung der sozioemotionalen Entwicklung bei Menschen mit geistiger Behinderung in ein Team. Psychiatrische Praxis, 42 (01)35-41. https://doi.org/10.1055/s-0033-1349565

Kratz, T., Heinrich, M., Schlauß, E., & Diefenbacher, A. (2015). Prävention des postoperativen Delirs – Eine prospektive Intervention mit gerontopsychiatrischer Liaisonpflege auf chirurgischen Stationen im Allgemeinkrankenhaus. Deutsches Ärzteblatt, 112(17), 289-296. https://doi.org/10.3238/arztebl.2015.0289

Sappok, T., Heinrich, M., & Underwood, L. (2015). Screening tools for autism spectrum disorders. Advances in Autism1(1), 12-29. https://doi.org/10.1108/AIA-03-2015-0001


Sappok, T., Gaul, I., Bergmann, T., Dziobek, I., Bölte, S., Diefenbacher, A., & Heinrich, M. (2014). The Diagnostic Behavioral Assessment for autism spectrum disorder - Revised: A screening instrument for adults with intellectual disability suspected of autism spectrum disorders. Research in Autism Spectrum Disorders8(4), 362-375. https://doi.org/10.1016/j.rasd.2013.12.016

Sappok, T., Heinrich, M. & Diefenbacher, A. (2014). Psychometrische Eigenschaften der Autismus-Checkliste (ACL) für erwachsene Menschen mit Intelligenzminderung. Psychiatrische Praxis, 41(01), 37-44. https://doi.org/10.1055/s-0033-1343193

Assessment Tools


Bergmann, T., Sappok, T., Dziobek, I., Ziegler, M., & Heinrich, M. (2020). MUSAD. Musikbasierte Skala zur Autismus Diagnostik. Bern: Hogrefe Verlag.


Sappok, T., Gaul, I., Bergmann, T., Dziobek, I., Bölte, S., Diefenbacher, A., & Heinrich, M. (2015). Der diagnostische Beobachtungsbogen für Autismus Spektrumstörungen – Revidiert (DiBAS-R). Ein Screening-Instrument für Erwachsene mit Intelligenzminderung und Autismusverdacht. Bern: Verlag Hans-Huber.